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Hang-Korng Ea Selected Research

octacalcium phosphate

2/2011Octacalcium phosphate crystals induce inflammation in vivo through interleukin-1 but independent of the NLRP3 inflammasome in mice.
1/2005Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes.

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Hang-Korng Ea Research Topics

Disease

30Gout
01/2022 - 05/2006
23Osteoarthritis
01/2022 - 01/2005
12Inflammation (Inflammations)
11/2020 - 05/2006
9Joint Diseases (Joint Disease)
01/2020 - 06/2004
8Pain (Aches)
11/2020 - 05/2004
6Chondrocalcinosis (Pseudogout)
01/2020 - 09/2005
6Arthritis (Polyarthritis)
01/2018 - 04/2012
5Gouty Arthritis
11/2019 - 07/2009
5Synovitis
06/2019 - 12/2012
4Rheumatic Diseases (Rheumatism)
11/2020 - 06/2007
4Chronic Renal Insufficiency
10/2020 - 12/2016
3Hemochromatosis (Bronze Diabetes)
07/2019 - 05/2013
3Calcinosis
12/2017 - 03/2014
3Calciphylaxis
12/2017 - 01/2016
3Hyperuricemia
12/2016 - 07/2009
2Crystal Arthropathies
10/2022 - 12/2012
2Knee Osteoarthritis
01/2022 - 01/2020
2Disease Progression
01/2022 - 01/2020
2Hypoxia (Hypoxemia)
10/2020 - 05/2016
2Hypertrophy
07/2019 - 05/2016
2Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2019 - 10/2015
2Infections
12/2018 - 12/2007
2Rheumatoid Arthritis
01/2017 - 02/2012
2Osteophyte
01/2017 - 02/2015
2Arthralgia (Joint Pain)
12/2012 - 10/2011
2Ankylosing Spondylitis
02/2012 - 05/2010
2Osteoporosis
09/2005 - 05/2004
1Hip Osteoarthritis (Coxarthrosis)
01/2022
1Poisoning
10/2020
1Diarrhea
10/2020
1Chronic Disease (Chronic Diseases)
10/2020
1Iron Overload
07/2019
1Knee Injuries (Knee Injury)
06/2019
1Osteoid Osteoma
02/2018
1Spontaneous Remission
02/2018
1Leukemia
01/2018
1Obesity
01/2018

Drug/Important Bio-Agent (IBA)

24Uric Acid (Urate)IBA
01/2022 - 06/2007
8Calcium PyrophosphateIBA
10/2022 - 06/2004
8calcium phosphateIBA
01/2013 - 06/2004
7ColchicineFDA LinkGeneric
10/2020 - 06/2007
6Interleukin-1 (Interleukin 1)IBA
12/2019 - 03/2009
56-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA
11/2020 - 12/2012
5InterleukinsIBA
11/2020 - 12/2012
5CalciumIBA
01/2020 - 03/2009
5Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
12/2018 - 07/2010
5InflammasomesIBA
01/2017 - 03/2009
4Metalloproteases (Metalloproteinases)IBA
06/2019 - 05/2016
3Matrix Metalloproteinases (MMPs)IBA
11/2020 - 05/2016
3sodium thiosulfateFDA Link
12/2017 - 01/2016
3CytokinesIBA
01/2017 - 05/2006
3Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
05/2013 - 02/2011
2GlucocorticoidsIBA
01/2022 - 12/2019
2Histones (Histone)IBA
11/2020 - 10/2011
2Interleukin-6 (Interleukin 6)IBA
11/2020 - 01/2017
2Adenosine Monophosphate (AMP)IBA
10/2020 - 01/2015
2Anti-Inflammatory Agents (Anti-Inflammatories)IBA
10/2020 - 06/2007
2IronIBA
07/2019 - 01/2019
2CollagenIBA
07/2019 - 01/2017
2Biomarkers (Surrogate Marker)IBA
06/2019 - 01/2015
2EpitopesIBA
06/2019 - 01/2013
2SugarsIBA
01/2017 - 12/2016
2EnzymesIBA
01/2016 - 01/2015
2Proteins (Proteins, Gene)FDA Link
02/2015 - 09/2011
2Hypoxanthine Phosphoribosyltransferase (Hypoxanthine Guanine Phosphoribosyltransferase)IBA
01/2015 - 07/2009
2C-Reactive ProteinIBA
01/2013 - 12/2012
2AdrenomedullinIBA
04/2012 - 05/2006
2Pharmaceutical PreparationsIBA
01/2012 - 10/2011
2PegloticaseFDA Link
01/2012 - 11/2011
2octacalcium phosphateIBA
02/2011 - 01/2005
1Dinoprostone (PGE2)FDA Link
11/2020
1Nerve Growth Factor (NGF)IBA
11/2020
1TransferasesIBA
11/2020
1Histone MethyltransferasesIBA
11/2020
1tazemetostatIBA
11/2020
1Glucose (Dextrose)FDA LinkGeneric
11/2020
1Deoxyglucose (2 Deoxy D glucose)IBA
11/2020
1tocilizumab (atlizumab)FDA Link
01/2020
1Transferrin (beta 2 Transferrin)IBA
07/2019
1Hemochromatosis ProteinIBA
07/2019
1Peroxidase (Myeloperoxidase)IBA
06/2019
1Indicators and Reagents (Reagents)IBA
06/2019
1Chondroitin Sulfates (Chondroitin Sulfate)IBA
06/2019
1Collagen Type II (Type II Collagen)IBA
06/2019
1Cartilage Oligomeric Matrix ProteinIBA
06/2019
1Aggrecans (Aggrecan)IBA
06/2019
1HDL LipoproteinsIBA
01/2019
1Amyloid (Amyloid Fibrils)IBA
01/2019
1Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA
07/2018
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2018
1FurinIBA
07/2018
1Matrix Metalloproteinase 13IBA
07/2018
1Diphosphonates (Bisphosphonates)IBA
02/2018

Therapy/Procedure

14Therapeutics
12/2020 - 06/2004
2Injections
01/2022 - 12/2017
2Contraindications
12/2019 - 12/2018
2Kidney Transplantation
12/2018 - 10/2017
2Intra-Articular Injections
01/2017 - 12/2012
1Replacement Arthroplasty
01/2020
1Arthroplasty
01/2020